Genomics

Biotechnology · Chapter 14 · 4. Bioinformatics

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Genomics: definition; structural and functional genomics; criteria for selecting an organism for genome sequencing
Types of sequences: cDNA, genomic DNA, ESTs and STSs; gene-finding software
Sequence analysis with BLAST and FASTA: global, local, pairwise and multiple alignment
Human Genome Project: objectives, participating countries, achievements and significance
DNA microarray technology (definition and application); single nucleotide polymorphisms